MTP 131 acetate
CAS No. 1334953-95-5
MTP 131 acetate ( Elamipretide Acetate )
Catalog No. M28051 CAS No. 1334953-95-5
MTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 88 | Get Quote |
|
5MG | 120 | Get Quote |
|
10MG | 192 | Get Quote |
|
25MG | 338 | Get Quote |
|
50MG | 501 | Get Quote |
|
100MG | 705 | Get Quote |
|
500MG | 1494 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMTP 131 acetate
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NoteResearch use only, not for human use.
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Brief DescriptionMTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.
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DescriptionMTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.(In Vitro):Pretreatment of cells with MTP 131 (acetate) inhibited H2O2?induced cytotoxicity and reduced LDH release in a dose?dependent manner, compared with cells treated with H2O2 alone. Mitochondrial depolarization and ROS generation were also prevented by MTP 131 (acetate) pretreatment. In addition, MTP 131 (acetate) pretreatment inhibited cytochrome c release from mitochondria to cytoplasm, and significantly reduced apoptosis in RGC?5 cells, compared with cells treated with H2O2 alone.(In Vivo):18-week-old db/db mice have reduced renal and cardiac superoxide levels, as measured by dihydroethidium oxidation, and increased levels of albuminuria, mesangial matrix accumulation, and urinary H2O2 Administration of MTP 131 (acetate) significantly inhibited increases in albuminuria, urinary H2O2, and mesangial matrix accumulation in db/db mice and fully preserved levels of renal superoxide production in these mice. MTP 131 (acetate) also reduced total renal lysocardiolipin and major lysocardiolipin subspecies and preserved lysocardiolipin acyltransferase 1 expression in db/db mice.
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SynonymsElamipretide Acetate
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1334953-95-5
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Formula Weight639.8
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Molecular FormulaC32H49N9O5?XC2H4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C=C(C=C1C)O)=C1C[C@H](NC([C@H](N)CCCNC(N)=N)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=O.CC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Polishchuk PG, et al. Application of random forest approach to QSAR prediction of aquatic toxicity. J Chem Inf Model. 2009 Nov;49(11):2481-8.
molnova catalog
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